The importance of being (a little bit) discrete
Posted by luca | On Friday, 9 August 2013
Title | The importance of being (a little bit) discrete |
Publication Type | Conference Paper |
Year of Publication | 2009 |
Authors | Bortolussi L, Policriti A |
Editor | Cannata N., Merelli E., Ulidowski I. |
Conference Name | Second Workshop From Biology to Concurrency and Back (FBTC 2008) |
Volume | 229 |
Pages | 75–92 |
Publisher | Elsevier |
Keywords | Biological Modeling, Discreteness, Hybrid Systems, Robustness, Stochastic Noise |
Abstract | We compare the hybrid, stochastic, and differential semantics for stochastic Concurrent Constraint Programming, focussing on the exhibited behavior of models and their robustness. By investigating in detail two case studies, a circadian clock model and the Repressilator, we comment on the effect of the introduction of a limited amount of discreteness in the description of biological systems with hybrid automata. Experimental evidence suggests that discreteness increases robustness of the models. |
URL | http://www.sciencedirect.com/science/article/pii/S1571066109000115 |
DOI | 10.1016/j.entcs.2009.02.006 |